How Have Clinical Trials Changed Over the Years?

Clinical trials are essential for improving the health of the general population through the creation of new treatments and drugs that could benefit humanity a great deal. Clinical trial consultants periodically test the effectiveness of new treatments and procedures to see if they work as intended and are better than previous medications.

Clinical trials have been running for hundreds of years however the way in which they have been conducted has changed dramatically. The introduction of data capture software and adjustment to trials with respect to the cohort being tested have improved the analysis of results and allowed for more definitive answers to whether or not new drugs are effective. Here we will discuss some of the major changes that have advanced the power of clinical trials and why these changes were made.

Inclusion

Historically, the representation in clinical trials hasn’t been very good with respect to gender and ethnicity. Recently there has been a large push to include a much wider range of ethnicities as well as having more women participating in clinical trials. This makes a lot of sense from a medical treatment point of view. Nowadays, there are a huge number of cultures living in the same society, so the clinical research being conducted should mirror this.

There’s no point in conducting clinical trials for a small demographic if it isn’t effective for the rest of society, as they will be left with poor medical treatment as a result. Information about the effectiveness of certain drugs and procedures needs to be gathered and analyzed for a wide range of ethnicities and genders, so decisions can be made about the best course of action for each individual. This aims to benefit the wider society and improve the overall health of humanity instead of just a single group which is a more fair and a better way to run things.

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Integrity of Research

Transparency of clinical trials is vitally important. It allows the public to gain access to the tests being conducted as well as the results gathered and provided. By allowing all of the information about a clinical trial to be available to anyone that wants to access it, the public can gain insight into why a trial is being conducted and what the results were. This encourages society to trust clinical research and recognize their importance in advancing overall healthcare.

When the data from clinical trials is kept hidden from the public, it builds skepticism and causes them to lose trust in the safety of the drugs being tested. When everything is laid out in front of them, they can make their own judgments and are much more likely to accept new treatments that may benefit them in the future.

There are a number of regulations required for clinical trials these days, which helps to maximize the safety of participants and allows them to fully understand what is going to happen in the trial. The ethical side of clinical trials has also improved vastly over the years where reporting and monitoring are required throughout the research. This again aims to improve the transparency of any clinical trial and removes bias and false data.

Efficiency

Efficiency-How Have Clinical Trials Changed Over the Years

The efficiency of clinical trials is another thing that has increased significantly. Thanks to the recent COVID-19 pandemic, the process of clinical trials has been optimized to gather results for treatments as fast, but as safely, as possible. These researches have been extremely successful in showing that clinical trials can be done at a much quicker pace without sacrificing integrity or safety.

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Ways in which the efficiency of clinical trials has been improved include things like online recruitment and online meetings that remove the need for in-person consultations in follow-up examinations. The pandemic showed that these steps were slow and unnecessary in obtaining the answers to the questions at hand and have become the normal protocol for a lot of clinical trials nowadays.

Data Sharing

When clinical trials first started, the data was usually only available to those involved in the study. What is clear now is that the more the research, data, and results are shared with others, the less likely the same trials will be repeated, wasting valuable time and resources. Sharing data also means more people will be looking at the same study and making suggestions on how to improve the trial or an alternative treatment option. Working together towards a common goal will always speed up the process with more people looking for answers to the same questions.

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