Health

Shift Work Sleep Disorder

June 27, 2023
SAHIL BATRA
Table of contents

Introduction

Shift Work Sleep Disorder (SWSD) is a condition that affects individuals who work outside the traditional 9-to-5 schedule, such as night shifts or rotating shifts. The disruption of the body’s natural sleep-wake cycle can have a significant impact on both physical and mental well-being. In this article, we will explore the causes, symptoms, and effective strategies for managing SWSD.

Understanding Shift Work Sleep Disorder

The circadian rhythm is an internal clock that operates on a 24-hour cycle and is responsible for regulating our sleep-wake cycle. Our bodies are naturally adapted to this rhythm. This rhythm is affected by external cues such as daylight and darkness, which send signals to our bodies to either be awake or asleep at the appropriate times. When people work outside of standard business hours, their sleep cycles frequently become out of sync with their circadian rhythms, which can result in shift work sleep disorder (SWSD).

Symptoms of Shift Work Sleep Disorder

  1. Insomnia: Difficulty falling asleep or staying asleep during scheduled sleep periods.
  2. Excessive sleepiness: Feeling excessively tired or drowsy during work shifts, compromising alertness and productivity.
  3. Fatigue: Despite sleeping during the day, individuals with SWSD often experience persistent fatigue due to the reduced quality of sleep.
  4. Difficulty concentrating: Lack of restorative sleep can impair cognitive function, making it challenging to concentrate and perform tasks effectively.

Treatment Approach for Shift Work Sleep Disorder with Armodafinil

Armodafinil: Mechanism of Action

Armodafinil, a derivative of modafinil, is a wakefulness-promoting agent that acts selectively on certain regions of the brain. It enhances wakefulness by affecting the neurotransmitters dopamine, norepinephrine, and histamine. By increasing the release of these neurotransmitters, armodafinil promotes alertness and cognitive function, while simultaneously reducing the sleep propensity.

Efficacy of Armodafinil in SWSD

Armodafinil has been the subject of a large number of clinical investigations, all of which have concluded that it is effective in enhancing wakefulness and cutting down on excessive drowsiness in those who have SWSD. Armodafinil was shown to significantly improve shift workers’ alertness and performance during night shifts in a randomized, placebo-controlled study including shift employees with shift work sleep disorder (SWSD). In addition to this, it improved the subjective indices of drowsiness and overall quality of life.

Dosage and Administration of Armodafinil

When treating shift work sleep disorder with armodafinil, the suggested dosage is normally between 150 and 250 milligrams to be given orally once a day, preferably an hour before the beginning of a shift. The dosage can change for each individual based on their answers and their needs. It is necessary to seek the advice of a qualified medical practitioner who can assess the particular requirements of the individual and offer suitable dosage counsel before one plans to buy modafinil online. It is crucial to have routine follow-ups to check the effectiveness of the treatment and, if necessary, alter the dosage.

Safety Profile and Considerations

Even though armodafinil is generally well accepted, there are a few precautions that should be taken, and it is vital to be aware of the potential adverse effects. Headache, nausea, inability to sleep, dry mouth, and anxiety are examples of common adverse effects; however, these symptoms are typically mild and very brief in nature. Anyone who has a history of liver impairment, psychological diseases, or cardiovascular concerns should exercise caution before initiating armodafinil medication and consult with a healthcare specialist first. Additionally, some prescription pharmaceuticals and armodafinil may interact negatively, which is why it is essential to inform your doctor about any dietary supplements and prescription prescriptions that you are currently using.

Combining Armodafinil with Sleep Hygiene Practices

It has been shown that armodafinil can effectively alleviate excessive sleepiness in patients with SWSD; however, the use of this medication must be accompanied by excellent sleep hygiene practices. The efficacy of armodafinil can be improved, and restful sleep can be promoted, by adhering to a routine, creating an environment that is calming, and practicing relaxation techniques. Additional practices that are considered to be good sleep hygiene include having a routine to follow before going to bed, reducing the amount of time spent in front of electronic devices, and avoiding stimulants in the hours leading up to bedtime.

Warning of Armodafinil Usage

Do not utilize armodafinil if you have previously experienced a skin irritation or hypersensitive response triggered by armodafinil or modafinil (Provigil).

Cease the usage of armodafinil immediately and contact your healthcare provider if you develop any type of skin rash, regardless of its severity. Additional indications of a severe reaction encompass fever, facial or tongue swelling, mouth ulcers, breathing difficulties, leg swelling, skin or eye yellowing, and the presence of skin rash or blistering sores.

Side Effects of Armodafinil

Although armodafinil is typically well tolerated, it has the potential to have side effects like any other prescription. It is significant to remember that not everyone experiences side effects, and that each person may experience side effects differently in terms of their severity and frequency. The potential adverse effects of armodafinil must be understood if you are to take it, and any worries should be brought up with your doctor. Armodafinil frequently causes the following adverse effects:

  1. Headaches: One of the most often reported side effects of armodafinil is headaches. They normally range from mild to moderate in intensity and gradually go weaker with time.
  2. Nausea: After using armodafinil, some people may develop nausea or an upset stomach. Usually transient, this adverse effect gets better with repeated use.
  3. Insomnia: Armodafinil promotes wakefulness and, if taken too soon before bed, can disrupt sleep. To reduce the risk of sleeplessness, it is advised to take armodafinil in the morning or as directed by your healthcare professional.
  4. Xerostomia: Sometimes referred to as dry mouth, might happen when taking armodafinil. Utilizing sugar-free gum or lozenges and staying hydrated can also assist to relieve this symptom.
  5. Anxiety and Nervousness: Armodafinil may occasionally make people feel more anxious or nervous. It is crucial to let your doctor know if you have any symptoms.
  6. Lightheadedness or dizziness: Some people who use armodafinil may experience lightheadedness or dizziness. It is advised to stay away from alertness-demanding tasks until you are familiar with how the medicine affects you.
  7. Elevated Heart Rate and Blood Pressure: Some people who take modafinil may have a modest increase in their heart rate and blood pressure. It is advised that blood pressure be checked frequently, especially for people with existing cardiovascular issues.

It’s crucial to keep in mind that these adverse effects are typically mild and scarce. However, it is important to speak with your doctor for an accurate assessment and recommendations if you suffer any uncommon or troublesome side effects while using armodafinil. They can evaluate your particular circumstance and decide the best course of action. 

Conclusion

People who work non-standard hours are more likely to suffer from shift work sleep disorder, which can have a substantial negative influence on both their quality of life and their performance at work. Armodafinil has emerged as an important therapy option, as it can successfully manage excessive drowsiness and improve wakefulness in people who have SWSD. Individuals can optimize their treatment outcomes and create a better balance between work and sleep by working closely with healthcare specialists and incorporating armodafinil into a comprehensive management plan that includes practices of good sleep hygiene. This type of strategy also includes armodafinil.