July 22, 2018 November 28, 2018
QUES 1. Poliovirus can most easily become more virulent by which of the following processes?
Mutation of the RNA genome at only a few positions
Recombining with another enterovirus
Altering its protein coat
Multiple nucleotide deletions and substitutions
QUES 2. What happens during the 'incubation period'?
The virus is cleared from the body by the immune system
This period commonly lasts for a few days
Virus replication happens at an intracellular level
This period commonly lasts for a few hours
QUES 3. What is the most common way for a virus to kill a cell?
Dissolves the cellular membrane
Fragments cellular DNA
Induces apoptosis via caspases
Totally blocks cellular transcription
QUES 4. Papillomaviruses cause warts and cancer but how do they most often infect humans?
Are water borne
Are Nosocomial and spread in hospitals
Via scratches and breaks in the skin
QUES 5. Many virus infections result in immune pathology, this is caused predominantly by which of the following?
Antibody mediated reactions
A response of killer T cells (CD-8)
A cytokine storm
A decline in function of the immune system
QUES 6. A special feature of adaptive immunity is:
Speed of response to a foreign protein
Ability to distinguish viruses and bacteria
Ability to distinguish self and non self
None of these
QUES 7. Interferons are very special defence mechanisms which operate by:
Binding to viruses
Binding to neighbouring cells
Inhibiting virus induced enzymes
Producing a long lasting state of resistance
QUES 8. Which of the following is the most special characteristic of the adaptive immune system?
Memory T cells
Very rapid response to infection
Clonal expansion of pre-existing antibodies and/or T cells
QUES 9. How are antibody producing cells stimulated?
Interacting with a T helper cell.
Interacting with a virus short peptide
Interacting with a virus infected cell
Interacting with a plasma cell
QUES 10. Cytotoxic T cells can be activated via which of the following?
By identifying virus peptides presented by antibodies
By reacting with budding viruses
By releasing complement
By identifying virus peptides presented by MHC-I
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